By Jie Jack Li
Greener than traditional equipment, C–H activation equipment have flourished over the past decade and turn into specifically appealing to natural chemists. Edited by way of a practioner during this quickly constructing box, C–H Bond Activation in natural Synthesis provides an summary of this fascinating playground of chemistry. The publication summarizes the state-of-the-art in C–H activation for functionalization, allowing you to hold out reactions within the so much environmentally pleasant style with the least infection of by-products.
The most well-liked C–H activation reactions are catalyzed by way of transition metals. This booklet dedicates a bankruptcy to every of the subsequent catalysts: palladium, rhodium, nickel, iron, copper, and cobalt. additionally, it covers radical-mediated C–H activation, fluorination through C–H activation, and C–H activation of heterocycles. utilizing a pedagogically functional strategy, every one bankruptcy is split by way of the transition steel catalyst, now not a selected transformation. this offers you an up to date assessment of crucial themes of C–H activation.
The sector of C–H activation has skilled a flurry of task during the last 20 years, so the time is correct for a source that summarizes those robust instruments with you could layout and build heteroaromatic molecules. therefore, direct C–H functionalization tools are anticipated to proceed to vastly give a contribution to the project of eco-friendly chemistry: low-energy, waste-free, and atom-economic adjustments for the synthesis of natural fabrics and biologically energetic molecules within the twenty-first century. utilizing this publication, you could perform environmentally pleasant reactions that permit the conversion of inexpensive and plentiful alkanes into worthy functionalized natural compounds.
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